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Difference Between IVF and ICSI | Which is Better IVF or ICSI

If you’re considering having fertility treatment in males and females then the two most popularly used treatments in Fertility Science: IVF(Female) and ICSI(Male). 

A Fine difference in IVF & ICSI.

IVF refers to ‘in-vitro fertilization, ICSI is intracytoplasmic sperm injection. Both provide an example of assisted conception.

IVF involves the collection of eggs from female patients by putting a needle across the vagina, and into the ovary, under the guidance of ultrasound. The procedure is performed with sedation, so you do not feel any discomfort. The eggs are mixed with the sperm in a dish, then inspected within 16-20 hours to check whether the sperm has naturally fertilized eggs. If the treatment has succeeded then the fertilized eggs will continue to develop in the laboratory over another two to five days prior to being placed in the womb. A pregnancy test is performed two weeks after egg collection to determine whether the IVF treatment was successful and the embryos have been implanted.

“ICSI is very similar to IVF however the difference lies in the stage of fertilization. Once the eggs have arrived in the lab, fertilization is achieved by injecting one normal-looking, active sperm, that is viewed under the microscope in each egg, using an extremely fine needle. The fertilized egg is placed in the womb, and the result can be confirmed by a pregnancy test within two weeks.”

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IVF Or ICSI: Which Treatment Should I Have?

IVF can be used as a treatment for a variety of fertility problems including issues with ovulation caused by polycystic Ovarian Syndrome or a genetic disorder or damaged, blocked, or missing fallopian tubes that are damaged or not functioning.

ICSI is more pertinent when it comes to male infertility issues. It is because the sperm is not required to work as hard as it does in natural fertilization, it is directly injected into the eggs. Male fertility issues could include the low number of sperm and low sperm mobility, or an excessive amount of abnormal sperm. ICSI is also a possibility when the sperm was frozen, or has been removed surgically from the epididymis or testis (for instance when it is the result of the vasectomy).

IVF or ICSI : Which is best?

The results of your initial fertility medical screening will help us to decide which type of fertility treatment is best for you. An individualized approach is essential to give you a clear picture of the highest chance of success. We take into consideration factors such as your medical history, age, and response to any previous cycles of treatment you may have had before.

Based on medical anecdotes many alternative options are available IUI, TESE, PESA or you may be recommended to go straight to IVF or ICSI if your partner’s semen analysis reveals a sperm disorder. Our focus is on helping you with your pregnancy, in the most effective way possible. All treatment decisions will be made in consultation with you under the guidance of our fertility experts so you must be fully aware of what your treatment path involves and your likely outcome, along with transparent costs.

The Cost Of Assisted Conception

IVF and ICSI can vary in price, depending on the complexity of the case and the individual needs of every patient. Our programs are tailored according to each bodily requirement providing a budget-friendly cost structure. Fertility World offers an affordable IVF package starting @ Rs.90,000 only. ICSI packages start from just @ Rs.20000 only

What is the relationship between IVF and ICSI related?

IVF, as well as ICSI, are the same in many ways, as long as eggs and sperm are retrieved from the person who donates or the partner. The embryologist fertilizes eggs on the morning of collection and then proceeds to select fertilized eggs the next day. Additionally, they are protected and inspected in incubators for up to five days. The best embryos are transferred into your womb to be placed.


This is a contentious issue in the field of reproductive medicine because it is thought that a lot of patients undergo ICSI even though they do not actually need to. ICSI is a highly efficient method of fertilization that lets you select the most attractive sperm. The average rate of fertilization is 70-80% in normal conditions. On the other hand, there is an additional artificial step that could be linked to health issues that could be a concern. Particularly, ICSI is linked to the possibility of contributing to an increase in the incidence of some imprinting diseases. In the Fertility World Center, when we carry out IVF, we particularly ensure that we don’t use ICSI when we don’t require it. Our belief is that fertilization naturally of normal sperm is less risky for the offspring and prevents the needless alteration of the eggs as well as fertilized sperm. If we’re worried that the sperm that appears normally would not be fertilizing the eggs, we could try ICSI on only half the eggs that are retrieved. Then we will try using the embryos that are fertilized in the traditional way initially and only then to use those that are from ICSI. ICSI group.

The History Of IVF And ICSI

The first baby born after the successful IVF procedure resulted in the UK in 1978. The procedure was created in the late 1970s by British nurses Jean Purdy, physiologist Robert Edwards as well as and obstetrician and Gynaecologist Patrick Steptoe. Couples were struggling to bear a child due to citing blockage of fallopian tubes. Similarly, the first birth that was successful with ICSI was recorded in 1992. The treatment was performed by Gianpiero Palermo following his research and developing the procedure at the Vrije University Brussels. Nowadays, ICSI is used in more than 60% of assisted reproductive treatment across the world and is frequently advised in cases of failure to fertilize in traditional IVF.

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